Most of the India’s population (about 75%) are lactose intolerant and can’t consume milk or milk products without feeling ill. This is because they lack the enzyme lactase, which digests the milk sugar lactose.
Lactose intolerance is inability to digest sugar in milk – lactose. Ability to digest lactose is significantly reduced among most individuals already from age two. When an organism ceases to digest lactose efficiently then consuming milk, dairy products, and other products that contain even a trace of lactose (e.g. bread, cereals, instant soups, nibbles…) can cause various symptoms in individuals such as abdominal pain, cramps, bloating, nausea, flatulence and diarrhoea. Lactose intolerance causes digestive problems that can significantly affect quality of life. If these symptoms occur in children they should not be ignored. About 20% of people consider themselves lactose intolerant because of related symptoms, although they have never been formally tested for the intolerance. It is important to distinguish between milk allergy and lactose intolerance. Milk allergy is an immune system response to milk, while lactose intolerance is a digestive disorder. Symptoms of lactose intolerance become evident in early childhood or in adolescence.
Lactose intolerance occurs when the lactase enzyme is not present in sufficient quantity to break down lactose. Genetic studies have shown that mutation at a single position in MCM6 gene is associated with decrease in lactase activity which may lead to lactose intolerance. Cytosine (C) or thymine (T) may be found at that position of gene, where C is associated with lactose intolerance and T is associated with lactose tolerance.
Genetic test (DNA test) for lactose intolerance is based on detection C or T variant in gene MCM6. Although this detection can be performed using several different methods, most of methods are technically demanding and expensive and some of them are also insufficiently precise.
Gluten: Some people experience symptoms found in celiac disease, such as “foggy mind”, depression, ADHD-like behavior, abdominal pain, bloating, diarrhea, constipation, headaches, bone or joint pain, and chronic fatigue when they have gluten in their diet, yet do not test positive for celiac disease. The terms non-celiac gluten sensitivity (NCGS) and non-celiac wheat sensitivity (NCWS) are generally used to refer to this condition, when removing gluten from the diet resolves symptoms.
Until now it was thought that people with NGCS/NCWS only experienced symptoms and did not have any intestinal damage. However, in July 2016, a team of researchers at Columbia University Medical Center, published a study confirming that wheat exposure in this group is, in fact, triggering a systemic immune reaction and accompanying intestinal cell damage. It is estimated that the impacted population is equal to or even exceeds the number of individuals with celiac disease (the vast majority of whom remain undiagnosed).
At this point, research has not confirmed that gluten is the culprit triggering the immune reaction as is the case with celiac disease. According to head researcher of the study, Dr. Armin Alaedini, “there is some ambiguity there, which is why we are referring to it as non-celiac wheat sensitivity for now.” He explains that “more studies are needed to understand the mechanism and identify the molecular triggers responsible for the breach of the intestinal barrier and the associated symptoms in affected patients.”
Genetic testing for celiac disease which is an autoimmune disorder requires a swab sample from the mouth or a blood sample. This testing can accurately predict the risk probability of the celiac disease along with the statistical probability of the individual’s offspring inheriting the same risk. A severe celiac disease is found to occur if both the parents are carriers of this gene. The testing also includes gluten sensitivity.
Detailed : Being a businessman, my work schedules are not definite. Due to poor dietary choices and unspecific meal timings, I suffered from a variety of health issues acidity, bloating and many other problems that used to affect my mental and physical condition and also affected my work. I used to visit doctors very often and used to get medications that were effective for a short period of time. But then the problems would start again. Then I heard about a genetic test, and how it can help overcome many health issues. When I did some research about it I found the best and affordable place to get it done from. I contacted GeneSupport. After the test, I got to know that the root cause of my various problems was my Gluten Intolerance. My counselors recommended a diet with little to no gluten intake. I cut down on my chapatis and within only a couple of days, started seeing results. Now I work happily with no health problems at all. I know what kind of lifestyle I need to lead. Thanks to GeneSupport for helping me get rid of the health issues I had.
Nutritionist counselling was helpful, my problem was understood, I was able to get to proper diet plan without settling for less taste. Diet plan has improved my appetite.
1) “Diet–gene interactions are highly complex and hard to predict, thus demonstrating the need for highly controlled genotypes and environmental conditions that allow for identifying different regulatory patterns based on diet and genotype. The challenges we now face may ultimately require a nutrigenomics project on the scale of the Human Genome Project in order to identify genes that cause or promote chronic disease and the nutrients that regulate or influence the activity of these genes.” – Dr. Jim Kaput, FDA National Center for Toxicological Research
2) “The new science of Nutrigenomics provides vital clues to new tools available for promoting good health and preventing and treating disease.” – Dr. Christine Houghton
GeneSupport is one of the pioneer companies in India, working to makes lives better using genes based personalized nutrition. The main backbone of our high-end services is the expert team we house. With years of experience in the field of Nutrigenomics, our experts – Dr. Geeta Dharmatti and Dr. R.D. Dixit are guiding the path to provide robust health and wellness services across the country.
Our genetic test involves a simple saliva or blood test. For this, you can choose to either visit our center or share your address with us to undertake doorstep delivery of the sample collection kits. The sample collection process is very easy; you just need to follow the basic steps mentioned on the kit. Once the sample is collected it is taken back to our lab and processed further. The results take a few weeks after which a detailed genetic report is prepared by our team. The report explains your diet plan and lifestyle modifications, which are followed by counselling by our experts.
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The occurrence of gluten intolerance in the Finnish population has doubled in the past twenty years. According to researchers, gluten intolerance may often be symptom-free, and people may be unaware that they have the condition if their symptoms are mild or atypical. Three out of four people with gluten intolerance have not been diagnosed, which also means that they are as yet going without treatment.
People with non-celiac wheat sensitivity have a weakened intestinal barrier, which leads to a systemic immune response after ingesting wheat and related cereals, new research confirms.
Researchers have found that taking an enzyme tablet while consuming foods containing gluten prevents a significant amount of it from entering the small intestine. This could enable gluten-sensitive patients to ingest small quantities of gluten without experiencing symptoms, such as bloating, diarrhea and abdominal pain.
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